Efficacy and safety of the DLL3/CD3 T-cell engager obrixtamig in patients with extrapulmonary neuroendocrine carcinomas with high or low DLL3 expression: Results from an ongoing phase I trial.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The protein misfolding and aggregation of α-synuclein (α-Syn) into neurotoxic amyloids ...

The growing burden of metabolic disorders manifested by hypertension, type 2 diabetes mellitus, hyperlipidemia, obesity and non-alcoholic fatty liver disease presents a significant global health ...

aInstitute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, Berlin, 13353, Germany ...

(🔥 New) Apr. 12, 2024. 💥 A better version of PixArt-Σ training & inference code, checkpoints are all released!!! Welcome to collaborate and contribute. Star 🌟us if you think it is helpful!! (🔥 New ...

This study provides important biophysical insights into the molecular mechanism underlying the association of alpha-synuclein chains, which is essential for understanding the pathogenesis of Parkinson ...

Efficacy, safety, and biomarkers of neoadjuvant niraparib monotherapy in homologous recombination deficiency (HRD) advanced ovarian cancer: A prospective, multicenter, phase II, single-arm NANT study.

The strongest force in the universe is called, aptly, the strong force. We never get to witness its fearsome power because it works only across subatomic distances, where it binds quarks together ...

(+)-α-Tocopherol is one of eight components of vitamin E and, while not the most abundant, it is the most biologically active. It occurs naturally in many foods, especially in plant oils such as wheat ...

Arvinas Operations Inc. has reported the development of diacylglycerol kinase α (DGK-α; DGKA) inhibitors reported to be useful for the treatment of cancer.

The multifunctional molecules mechanistic target of rapamycin (mTOR) and α-ketoglutarate (αKG) are crucial players in the regulatory mechanisms that maintain cell homeostasis in an ever-changing ...