Zimbabwe introduces lenacapavir, a new HIV prevention drug administered twice a year, offering hope for high-risk groups but ...

Officer-involved shooting under investigation by Indianapolis Metropolitan Police Department. No offices injured. More ...

Crews recover bodies of nine backcountry skiers killed in a California avalanche. Intense snowfall and threat of more ...

Beware of vehicle fraud cases in Indiana as scammers use fake titles and VINs to sell stolen cars. Learn how to protect ...

A male juvenile is in critical condition after a shooting in Fort Wayne. No information on the suspect or victim's identity.

President Trump approves emergency assistance to Washington, D.C. for a sewage system leak that dumped 250 million gallons of raw sewage into the Potomac River.

Pittsburgh holds off Notre Dame 73-68 with Roman Siulepa's 22 points. Panthers end five-game skid, Notre Dame struggles ...

Michigan claims the top spot in the AP Top 25 poll and receives the No. 1 seed in the NCAA Tournament. Duke, Arizona, and ...

Young woman dies in head-on collision with wrong-way driver on I-65. Driver suspected of impairment. Investigation ongoing.

Get the latest weather forecast for Indianapolis. Expect light snow, cold temperatures, and gusty winds. Mild temperatures return by midweek.

Investigation underway after a 20-year-old male was shot in Elkhart. Male transported to hospital, condition unknown. Police ...