We combine advanced technologies such as spatial transcriptomics, multiplexed imaging, and in situ sequencing to map cellular components in their native tissue context. Obtain high-resolution data ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

In this GEN Learning Lab, our expert panelists Linda Orzolek, MS, MB, Xuhuai Ji, MD, PhD, and Christina Chang, PhD, will discuss the current landscape of imaging- and next-generation sequencing-based ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

"Population-scale spatial has arrived and is on center-stage at AGBT 2026," stated Christopher Mason, PhD, Professor of Physiology and Biophysics at Weill Cornell Medicine. " [Jiwoon Park] is ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.