Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...
Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...
Sarah J. Aitken is at the Center of Molecular and Cellular Oncology, Yale Cancer Center, New Haven, Connecticut 06511, USA, and in the Department of Pathology, Yale School of Medicine, New Haven. Read ...
The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results