A study shows mitochondrial electron flow keeps dendritic cells primed, regulating gene activity and T-cell activation. The ...
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...
In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...
NUFIP1 in Sepsis: Regulating Immune Function and Organ Dysfunction. This illustration demonstrates the pivotal role of NUFIP1-mediated ribophagy in dendritic cell activation and sepsis-induced immune ...
The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...
Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...
The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...
Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the Institute for Research in ...